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Charles River Laboratories opened a 450,000-sf preclinical research center in Reno, Calif., in fall of 2007. Sited in Truckee Meadows, the BSL-2 facility is among the five largest animal testing laboratories in the country and accommodates drug research on rodents, dogs, and monkeys. Charles River invested $107 million to renovate the facility, not including laboratory equipment. The first floor houses a large chemical laboratory and the 50,000-sf second floor houses animal research. The center employs 400 staff members with a projected 900 employees in a few years.