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M.D. Anderson Cancer Center has topped out its new $221.9-million George and Cynthia Mitchell Basic Sciences Research Building. Slated for completion and initial occupancy in November, the 18-story, 500,000-sf facility is expected to be fully operational in June 2004. Located in Houston's Texas Medical Center, the building will house six floors of research laboratories, an auditorium, conference facilities, small-animal vivariums, and classrooms for the University of Texas Graduate School of Biomedical Sciences at Houston.