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GlaxoSmithKline has completed a $13-million  cGMP upgrade of the Tums(R) manufacturing site--the only such facility in the world. McCarthy performed upgrades to the 70-year-old plant, which produces 10 billion tablets annually. Designed by architect Lockwood Greene Engineers, of Spartanburg, S.C., these upgrades affected every aspect of the manufacturing process, from raw material handling through packaging. The phased construction included installation of a new "super sack" material handling system, dust collection systems and electrical and chilled water capacity increases.