Pharmaceutical Development Initiative Building #314
Occupancy: October 1996
Published November 1997
A new design trend is emerging in R&D facilities stressing convertible laboratory-research areas to emphasize interaction among staff and researchers. At the newly renovated R&D facility for Eli Lilly and Company, this new design promotes interaction among scientists and brings varied research and development functions together with its flexible, modular, team-oriented lab units. The Pharmaceutical Development Initiative Building #314 arranges labs to accommodate commonplace meetings which encourage staff to share ideas and practices.
Eli Lilly and Company's $52-million renovation of a five-story, 425,000-sf building houses new lab and research support areas for teams of scientists. Originally built as an automobile manufacturing plant in the 1920s, the renovation and construction of 40,000 sf of new space, converted existing lab, storage and cafeteria space into new state-of-the-art laboratories and formulation areas for more than 400 researchers and staff.
Nearly every lab unit can be appropriate for nearly any project without significant refit of space due to a minimum of fixed casework. Placing the emphasis on moveable tables and shelving with overhead utility service columns allows the labs to be configured in a myriad of ways. Modular formulation areas near the labs bring bench scale development and pilot scale development into one facility. The formulation labs are used by any of the research teams for development studies up to and including production of clinical trial material.
The primary challenge of the 600-foot long building was air distribution, both supply and exhaust. Without consuming large amounts of floor area or creating too many separate systems, two new large HVAC chases are placed at the ends of the building where air supply fans, ductwork and exhaust fans are located.
Exterior renovations consist of an all-new precast concrete skin and window system to update its appearance and, most importantly, to provide a weather-tight overcladding for the existing aging concrete frames. New stair towers and a five story atrium added to the building provide circulation and interaction areas to reinforce the notion of a synergistic, team-oriented workplace. The interior, likewise, reinforces team interaction with copy centers, conference rooms, coffee stations and a deli concentrated at the center of the building to coax people into places where chance meetings become commonplace.
| Building Owner: |
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Eli Lilly and Company |
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Owner Contact:
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Fritz Frommeyer or Dave Needler, Facilities Delivery Engineering
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Building Location:
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Indianapolis, IN UNITED STATES
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Project Type:
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New Construction,Renovation
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Principal Building Function:
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Development labs for pharmaceutical products |
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Project Delivery Method:
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Fast Track
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Project Timeline
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| Apr 1994 | Planning Start |
| Jul 1994 | Design Start |
| Apr 1995 | Construction Start |
| Oct 1996 | Completion |
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Last known status: Completed
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| Project Cost: |
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$53,000,000 |
| Construction Cost: |
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$40,000,000 |
| Cost Per Sq. Ft: |
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$133 |
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About These Cost Figures
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Project Includes:
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Laboratory: Dry And Wet
Office
Pilot Plant
Product Development
R&D
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| Total GSF: |
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425,000 |
| Total NSF: |
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190,282 |
| Efficiency: |
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62% |
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Building Population:
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450
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People Density:
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944 gsf/person
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Building Services:
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Vacuum, compressed air, N2,house vacuum, process hot and cold water, 30 psi steam, potable H&C H2O
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Special Equip:
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NMRs, LC Mass Spectrometers, GC Mass Spectrometers, FTIR, Fluid Bed Dryers, Coating Pans, Tray Dryer, Environmental Chambers, Lyophilizers, Atomic Absorber, Spectrophotometer, Electron Microscopes, Robotics
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Office Size:
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144/120/64 NSF
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Power Req:
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24.30 total watts/nsf
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HVAC Req:
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2 cfm/nsf
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Structure/Foundation:
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Existing structure
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Casework Mat'l:
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Metal; mixture of fixed and movable tables; movable and adjustable shelving systems
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Fume Hoods:
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75, 5'hoods
three 6' hoods
two 8' walk-ins
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Biosafety Cabinets:
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16, 6' class II, type B2
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Architect
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Flad Architects
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Consultant
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Affiliated Engineers Inc. (AEI)
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Supplier - Biosafety Cabinets
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NUAIRE Inc.
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Supplier - Furniture
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Fisher Hamilton
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| Profile Created 11/01/1997 |
| Last Updated 04/04/2006 |
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The cost figures reported are supplied by the firms that submitted these
projects for publication, which in most cases are the designers or builders.
Whereas these sources are intimately familiar with their projects, they may
not be fully aware of the owners' finally-realized and recorded costs. In some
cases, costs are truly and completely accounted for, and in others they represent
a near approximation of the final costs. Costs have not been adjusted for
year of construction, nor has any attempt been made to make regional cost
adjustments.
Further, costs are not comparable on any kind of detailed standard costing model.
Hence, it is possible for the cost of one building to include a steam boiler, while
the cost of a comparable building might not include the boiler, if steam is being
supplied from an already existing campus grid. Or, in another case, a building might
include excess boiler capacity to supply steam to another building. Some submittals
include fees or unusual site improvements as part of the construction costs, which
others do not.
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Exterior The newly renovated R&D facility for Eli Lilly and Company incorporates an innovative design stressing interaction among staff and researchers. By opening lab formulation areas, chance meetings and encounters become routine. Photo courtesy of Hedrich Blessing. Notes:
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