This is Mayo's first hospital designed and built from the ground up. Four stories of the five-story facility are complete, with the fifth shelled for future expansion. Total project cost for the hospital is $114 million, bringing Mayo's total investment in the Paradise Valley to more than $300 million.

Geometric forms and earth tones in the building's design relate to the surrounding 210-acre desert campus, including the McDowell Mountains located to the northeast. The main lobby features a five-story atrium flooded with natural light, landscaped with live greenery, and a tumbling sandstone fountain. The lobby is clad in green sandstone, contrasting with the neutral brown tones on the exterior. Balconies on each floor of the hospital overlook the atrium. Every patient room has a windowed view, either to the outside or into the interior atrium.

All patient services are conveniently located in the front of the hospital so patients and the family members accompanying them can quickly find whatever they need. The emergency department and urgent care are located on the west side of the building. A pharmacy, medical records, and volunteer services complete the first floor.

The 178 patient rooms, all of which are private, are clustered in groups no larger than 12 beds each. These spaces as well as the entire hospital are pre-wired for telemetry so that monitoring of heart and other vital signs can be accomplished from any patient room.

Special accommodations for accompanying family members include a business center equipped with fax and telephone, shower facilities in the intensive/critical care waiting area, and vending machines, coffee makers, and microwaves in the visitor lounges.

A 36,000-sf surgical suite on the second floor contains 14 operating rooms for inpatient and outpatient surgery. Also included on the second floor are the intensive care/critical care unit, the short-stay recovery unit for outpatient surgery, and a sleep studies lab. The third floor is devoted to sub-acute care, rehabilitation, physical therapy, as well as medical/surgical beds for urology, orthopedics, and neurology/neurosurgery patients. The fourth floor houses additional patient rooms, inpatient dialysis, the oncology unit, and a transplant facility.