The facility, erected on the north central part of the campus, takes full advantage of the hillside to allow for a basement to house the animal vivarium. The main ground floor entrance opens onto a two-story gateway for the biocomplex courtyard and permits easy access to the building's administrative offices. The main floor houses a large seminar room, faculty offices, an NMR suite and two wings of main laboratory space. A three-story atrium serves as the focal point of the core area.

The second and third floors house labs and faculty offices. Specialty and core support labs are placed at the crossing of each floor and open onto the central atrium.

Specialty components at the Institute for Bioengineering and Bioscience include a magnetic resonance laboratory, cell culture facilities, an x-ray diffraction laboratory, a vivarium and a biomodeling laboratory for computational approaches to problems in biology and medicine. Typical labs provide equipment for research in bioscience, tissue cultures, synthetic and organic chemistry.