Each level is designed to accommodate 96 students in an open floor plan, allowing maximum visibility throughout the laboratories. In the organic lab, each pair of students shares a glass-walled fume hood that allows all experiments to be performed within the safety of the hood. The instrument room, in the center of the floor, is walled with glass on all four sides to allow easy supervision within the open plan design.

In the general chemistry lab, student stations are arranged in groups of eight in a cruciform plan. Each pair of students shares a computer located at the center of the cruciform bench, where the individual student stations meet. Accessible hoods and work stations are ADA compliant on each floor.

Fume hoods are also provided on the perimeter of all laboratories with adequate space for pouring and dispensing of chemicals. Shared bench space for small instruments is located throughout each floor in addition to three "safety stations" equipped with emergency showers, emergency telephones and first-aid kits.

Each floor is provided with its own fan-room, incorporating a single custom-built variable speed air handling unit operating in conjunction with the roof-mounted exhaust fans to maintain negative pressure under all conditions. The fan room walls are built of solid concrete masonry with additional interior lining to contain fan noise.

In the organic chemistry lab, a laminar down flow supply system successfully delivers draft-free make-up air necessary for the safe operation of the 57 fume hoods on the floor. When all hoods are operational, the air change rate is in excess of 50 changes per hour. Fume hood safety requirements include working in pairs to complete all laboratory experiments.