The University of Pennsylvania began construction in early 2022 on the $173 million Vagelos Laboratory for Energy Science & Technology in Philadelphia. Designed by Behnisch Architekten, the seven-story, 110,000-sf facility will enable investigators from the School of Arts and Sciences and the School of Engineering and Applied Sciences to discover new solutions for energy generation, storage, and management. Leveraging sophisticated strategies for the mitigation of vibration and electromagnetic interference, the highly flexible structure will provide research labs for optics and wet chemistry, an NMR spectrometry suite with helium recovery, collaboration spaces, write-up areas, and faculty and administrative offices. Radiant heating and cooling systems will enhance the building’s energy performance, with sophisticated mechanical infrastructure supplying safe and appropriate airflows. An exterior façade with integrated shading devices will cut off solar angles to maximize natural light while minimizing glare. Targeting a minimum of LEED Silver certification, the sustainably designed project is slated for occupancy in fall of 2024.