Engineered openings that minimize the turbulence of transfer airflow, along with a mix of control strategies between labs and anchor spaces, are a best practice for achieving stable pressurization in biocontainment facilities. “The golden rule of containment is to always maintain the relationship between exhaust and supply,” says Michael Clements, director of life sciences at WorkingBuildings, LLC. “To keep a room contained, airflow fluctuations in the exhaust require a reaction in the supply in order to maintain this critical relationship.”

In the concluding Open Forum/Town Hall session of Tradeline’s Facility Strategies for Animal Research and Biocontainment conference, moderator Derek Westfall, president of Tradeline, and subject matter commentators, Mark Corey with Flad Architects and Tiffini Lovelace with EYP Architecture & Engineering, led a knowledge exchange on questions posed by conference attendees. This is an edited transcript of that exchange.