The need for new healthcare professionals is increasing demand for health science education and research space, and facility planners are facing a wide range of challenges and opportunities in meeting that demand. In this case study of the USF Health Morsani College of Medicine, session leaders examine facility design solutions that meet the needs of the rapidly changing healthcare environment, accommodate new technologies, learning styles and growth, and foster inclusion and wellness. They provide guidance for institutions navigating critical issues for health education, including planning metrics for adaptable, tech-infused spaces, developing work-ready students for ever-evolving health professions, and driving revenue through shared space and resources.