Adaptive reuse is an increasingly attractive options for institutions tasked with accommodating program growth and strategically managing physical resources and capital. Session leaders examine the positive aspects of facility renovation and adaptation approaches, including attractive locations, “good bones”, sustainability, and cost, as well as workarounds for negatives including floor to floor heights, infrastructure, and floorplate sizes. They provide case studies from University of Wisconsin and Northwestern University and illustrate the kind of research spaces that can be created as well as solutions for historic building limitations.