Many university campuses are hamstrung by buildings past their useful life – costly-to-operate eyesores incompatible with modern program priorities. The question is, what is the best path toward renewal? Session leaders examine four project case studies from different institutions to demonstrate best practices, methods, and tools for assessing facility conditions and physical space configurations to optimize decisions about capital reinvestment. They illustrate trending metrics for sustainability, suitability for program use, first cost, and life-cycle costs, and identify common themes across building types, integrative methodologies comparing renewal options, and challenges and tradeoffs associated with renewal.