Manufacturing

Tonix Pharmaceuticals broke ground in August of 2021 on the 45,000-sf Advanced Development Center in Dartmouth, Mass. Enabling the production of clinical-stage vaccines for COVID-19 and other infectious diseases, the BSL-2 facility will utilize single-use bioreactors and purification suites for optimal efficiency and flexibility. The cGMP center will also offer state-of-the-art research, development, and analytical suites. Approximately 70 scientists, technicians, and manufacturing staff will work in the turnkey building. 

The Fitzsimons Innovation Community broke ground in August of 2021 on Bioscience 5 in Aurora, Colo. Strategically located next to the University of Colorado Anschutz Medical Campus, the 90,000-sf building will enable biomedical and pharmaceutical tenants to manufacture next-generation cell and gene therapy products on a commercial scale. Saunders Construction is the general contractor for the highly flexible facility, which is slated for occupancy in spring of 2022.

Precision NanoSystems is constructing its global headquarters in Vancouver, British Columbia. Located in the four-story Evolution Block building, the 75,000-sf leased facility will feature a GMP biomanufacturing center for the production of genetic medicines and RNA-based therapeutics. The federal government has contributed CAD$25.1 million in funding towards the project's construction to increase the nation's domestic supply of COVID-19 vaccines and prepare for future pandemics.

Landmark Bio began construction in July of 2021 on a leased facility in Watertown, Mass. Supported by $76 million in funding, the 40,000-sf project will accelerate the availability of novel therapeutics by collocating research, development, manufacturing, and commercialization activities in the same structure. Featuring eight GMP cleanrooms configured to allow production of both cell and viral vector materials, the center will include labs, offices, and quality control suites.

GE Aviation broke ground in June of 2021 on an advanced manufacturing center in Beavercreek, Ohio. Sited on 53 acres in the Miami Valley Research Park, the 280,000-sf structure will enable the development and production of gas turbine engine components and mechanical systems for a variety of industries, including aviation, space, defense, oil, and gas. Integrating high-performance glazing and insulated concrete wall panels, the steel-framed facility will leverage lean manufacturing technologies to optimize efficiency and reduce waste.

Nexus Pharmaceuticals opened a $100 million manufacturing facility in July of 2021 in Pleasant Prairie, Wis. Increasing the nation's domestic supply of life-saving medicines, the 84,000-sf structure will produce specialty and generic injectable drugs, including vaccines for COVID-19 and other infectious diseases. The three-story building features an advanced isolator system and multiple lyophilization machines to ensure maximum product protection and sterility.

General Motors is planning to construct a $71 million R&D campus in Pasadena, Calif. Replacing an existing facility in North Hollywood, the 149,000-sf complex will provide GM's Advanced Design Center with multidisciplinary engineering labs for the discovery of new mobility solutions. The collaborative research center will provide the latest tools, equipment, and workspaces that have been tactically designed to foster synergy and ideation, including:

AbCellera Biologics is planning to break ground in late 2021 on a manufacturing plant for therapeutic antibodies in Vancouver, British Columbia. Supported by $175.6 million in federal funding, the 130,000-sf project will cost approximately CAD$240 million to build. Offering advanced production suites, labs, offices, and warehouse space, the GMP facility will enhance the country's ability to create vaccines in response to future pandemic threats.

Moderna is initiating a major expansion of the 300,000-sf Moderna Technology Center in Norwood, Mass. Providing additional production capacity for mRNA vaccines and therapeutics, the 350,000-sf project will include the acquisition of a 240,000-sf structure and the renovation of existing buildings. Enabling a 50 percent increase in the plant's commercial COVID-19 vaccine output by early 2022, the new facilities will also support the creation of thousands of preclinical research samples per month.

Nanotronics opened its 45,000-sf headquarters and manufacturing hub in May of 2021 at the Brooklyn Navy Yard in New York. Seamlessly integrating research, development, and production activities, the technology-rich facility supports the creation of smart factory hardware and software that combines robotics, optical microscopy, artificial intelligence, and machine learning platforms.

The International Society for Pharmaceutical Engineering has announced the 2021 Facility of the Year Awards category winners. The awards include:

Sanofi will begin construction in fall of 2021 on a vaccine manufacturing facility in Singapore. Representing an investment of $477 million over five years, the structure will comprise a central hub housing several fully digitalized modules that allow production of three to four vaccines simultaneously. Designed for maximal flexibility, the next-generation factory will integrate multiple technology platforms based on different cell types, allowing the delivery of specific vaccines to be prioritized according to public health needs.

Vibalogics is creating a 110,000-sf facility for the production of oncolytic viruses, viral vector vaccines, and viral vector gene therapy products in Boxborough, Mass. Supporting late-phase clinical and commercial manufacturing operations, the highly flexible structure will include 2,000-liter bioreactors, multiple cGMP production suites, offices, warehouse space, and labs for research, development, and quality control. The $150 million project involves the renovation of an existing R&D building previously occupied by Cisco Systems.

Civica Rx began construction in early 2021 on a $124.5 million pharmaceutical manufacturing center in Petersburg, Va. Created in collaboration with Phlow Corp., the 120,000-sf plant will produce sterile injectables for the treatment of COVID-19, emergency room and intensive-care unit treatments, surgeries, and other serious conditions. The facility will feature steam sterilization capabilities, disposable technologies, and advanced automation systems for visual inspection and packaging.

Universal Robots is partnering with Mobile Industrial Robots to create a research and development campus in Odense, Denmark. Designed by 3XN to promote knowledge exchange and enhance employee wellbeing, the 215,000-sf Cobot Hub will offer flexible modules that can be tailored to provide the two companies with specialized labs, workshops, maker spaces, and open office environments.