Animal Research

A comprehensive renovation of Harvard University’s 105,000-sf Sherman Fairchild Building for the Stem Cell and Regenerative Medicine Department has allowed researchers to work more efficiently and collaboratively than ever before, with shared fume hoods and environmental, imaging, and equipment rooms. High-use support spaces, such as tissue culture rooms, were moved to the building exterior to take advantage of natural light, while the other shared spaces were moved to the interior.

Tata Memorial Centre has opened a cryogenic mouse embryo storage bank in Mumbai. Located at the Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), the facility will preserve valuable genetic strains of laboratory rodents to support biomedical research by the Laboratory Animal Facility (LAF). Cryopreservation enables the storage of biological material at extremely low temperatures for long periods of time. The LAF maintains 22 different strains of mice as well as two strains of hamsters, one strain of rats, and one rabbit strain.

The $270 million Albert Sherman Center expands and unifies the UMass Medical School’s Worcester campus, doubling its research capacity and supporting the school’s new learner-centered curriculum. The 512,000-sf state-of-the-art interdisciplinary research and education facility fosters interaction and collaboration among scientists and promotes innovation and synergies across disciplines, bringing together researchers from one research building and several smaller satellite buildings and leased spaces.

The Coachella Valley Mosquito and Vector Control District is constructing a new BSL-3 laboratory, to be completed in March 2014, to reduce turnaround time on mosquito testing by bringing currently outsourced procedures in-house. The District is dedicated to arbovirus (arthropod-borne virus) surveillance, focusing on mosquito abundance, mosquito infections, and avian infections to target mosquito control in areas that are the most important to preventing disease transmission. By limiting mosquito control to selected areas, the District lowers expense, time, and labor, and minimizes harm to the environment.

The following is a condensed transcript of a panel discussion from Tradeline’s 2013 International Conference on Research Facilities. The panelists are William Gustafson, principal at Ballinger; Steven Frei, principal at Affiliated Engineers, and Michael Reagan, vice president of Stantec. The moderator is Steve Westfall, founder and CEO of Tradeline.

The Australian Animal Health Laboratory (AAHL), a high-containment facility in Geelong, Victoria, has been operating 24/7 with no shutdowns, even for maintenance or upgrades, for nearly 30 years, thanks to the initial design, selection of materials, and quality of construction.

The AAHL—with BSL-2, BSL-3, and BSL-4 biocontainment areas—has an extensive redundant plant to ensure that critical systems, such as the air handling units, remain continually operational. The facility was one of the first in the world to use microprocessor control for all engineering systems.

AgriBio, Centre for AgriBioscience is one of Australia's premier biosciences facilities, with a key emphasis on supporting and protecting Victoria's $8.4 billion (USD) agricultural sector by focusing on cutting-edge research to improve productivity, fight disease, and reduce environmental impact. The state-of-the-art research facility serves joint venture partners La Trobe University (La Trobe) and the Victorian Department of Primary Industries (DPI).

The University of Edinburgh opened the first phase of the National Avian Research Facility in early 2013. The $7.9 million facility is part of a collaborative two-building research campus currently under construction for the Roslin Institute of the Royal (Dick) School of Veterinary Studies and The Pirbright Institute. Ground was broken on the project in early 2013. Phase two of the $22 million project is expected to open in late 2014.

Non-residential construction volumes and pricing continued their upward trend in the second quarter, with prices increasing an average of 2 to 4 percent in the first half of 2013. These factors, along with growing market confidence and a narrowing labor supply, will continue to push new construction costs closer to the trend line for the near to medium term.

Washington State University’s three-story, 62,000-sf Paul G. Allen Center for Global Animal Health is the first of a two-phase project dedicated to infectious disease research and animal diagnostics. It houses the Paul G. Allen School for Global Animal Health, which provides innovative solutions to global infectious disease challenges through research, education, global outreach, and application of disease control at the human-animal interface. The second phase will be completion of the Washington Animal Disease and Diagnostic Laboratory.

The University of Georgia is building the $97.7 million Veterinary Medical Learning Center (VLMC) in Athens, Ga. Providing five buildings and approximately 300,000 sf for the College of Veterinary Medicine, the campus will include an academic building, a teaching hospital, a covered arena, a large animal isolation barn, and a theriogenology and farm field services building. Ground was broken on the project in November of 2012 and construction began in March of 2013. Completion is expected in 2015.

The new ANSI Standard Z9.14-201X will govern the testing and performance verification methodologies for ventilation systems for BSL-3 and ABSL-3 facilities. High containment laboratory verification is the systematic review and evaluation of all safety features and processes associated with the laboratory, including engineering controls, personal protective equipment, SOPs, administrative controls, and building and system integrity.

Texas A&M University is building an 11,000-sf research aviary for the College of Veterinary Medicine & Biomedical Sciences. Located in College Station, the facility will include a biocontainment laboratory, a bird hospital, quarantine suites, two isolation rooms, classrooms, and administrative offices. Completion is expected in May of 2014.

The American National Standards Institute (ANSI) will be collecting comments through Sept. 10 on its new standard, Testing and Performance-Verification Methodologies for Ventilation Systems for Biosafety Level 3 (BSL-3) and Animal Biosafety Level 3 (ABSL-3) Facilities, also known as ANSI Standard Z9.14-2013. The 127-page document provides guidance for the inspection and testing of ventilation system components of new or existing BSL-3 and ABSL-3 laboratories, including research, pharmaceutical, and insectary facilities.

The 33,000-sf Clara Christie Centre for Mouse Genomics (CCCMG) at the University of Calgary—a centralized facility for the production and breeding of transgenic mice—expands mouse housing, provides procedure spaces for researchers, enables mouse transgenics production, and creates new space to phenotype the transgenic models.