Pharmaceutical

Winstanley Enterprises is planning to build a $100 million bioscience research building in New Haven, Conn. Designed by Elkus Manfredi Architects, the 10-story, 500,000-sf facility will provide leasable laboratory and office environments for life science companies and academic institutions. Featuring a large public plaza, the project will include a conference center, a 50,000-sf business incubator, and a classroom for K-12 educational programs.

MilliporeSigma, a subsidiary of Merck, is planning to expand its existing campus in Buchs, Switzerland, with the construction of a $20 million laboratory for the company's reference materials business. Accommodating 40 employees, the three-story, 12,000-sf structure will provide analytical and R&D suites for the testing of pharmaceuticals, environmental materials, and food and beverage products.

SiO2 Materials Science is investing $163 million to expand its production capacity for vaccine vials and syringes in Auburn, Ala. The company will increase the footprint of its existing facility in the Auburn Technology Park West to create a 70,000-sf manufacturing center with additional space for precision injection molding operations. A second molding plant will also be constructed nearby. 

University Hospital Hamburg-Eppendorf is planning to build a 193,000-sf translational medicine hub in Hamburg, Germany. Housing the Campus Research II facility and the Hamburg Center for Translational Immunology, the interdisciplinary complex will provide 150 labs for the study of inflammation, infection, and immunology. The structure will also accommodate collaborative workspaces, instrumentation suites, research offices, and interaction zones.

AstraZeneca is planning to expand its Hurdsfield campus with the construction of a 95,000-sf pharmaceutical manufacturing facility. Accommodating 72 new employees, Building 52 will occupy a remediated brownfield site in Macclesfield in the United Kingdom. The two-story structure will provide leading-edge formulation suites and production lines for the manufacture of prescription medicines.

Grand River Aseptic Manufacturing (GRAM) opened a $60 million facility for injectable fill-and-finish operations in June of 2020. Tripling GRAM's existing footprint in Grand Rapids, Mich., the 61,500-sf expansion provides a Grade C cleanroom, two formulation suites, and 14,000 sf of shell space to accommodate future growth. The facility leverages leading-edge automation technologies and high-speed instrumentation to accelerate the production of parenteral therapies. The project was delivered in just 20 months by design-build contractor CRB.

Trammell Crow Company will break ground in July of 2020 on Fulton Labs in Chicago. Providing wet and dry research environments, the 16-story, 423,454-sf life science facility will offer column-free and long-span layouts as well as a dedicated innovation floor for early-stage companies. Designed for maximum flexibility and scalability, the 16-story structure will integrate advanced mechanical infrastructure to support advanced R&D enterprises, with all labs meeting VC-A vibration criteria to ensure reproducible research results.

Sanofi Pasteur is planning to create the Evolutive Vaccine Facility (EVF) in Neuville sur Saône, France. Representing an investment of €490 million over a five-year period, the structure will house a central unit containing several fully digital production modules, enabling the manufacture of four vaccines simultaneously. This modularity will make it possible to prioritize the delivery of a specific vaccine to address crucial public health issues. The company will also invest €120 million to construct a new R&D center in Marcy-l'Etoile.

The South Australian Health and Medical Research Institute will begin construction in July of 2020 on the SAHMRI 2 building in Adelaide. Designed by Woods Bagot, the AUD$500 million project will accelerate the delivery of leading-edge clinical care as well as accommodating growing research programs in health analytics, artificial intelligence, and machine learning. Standing 12 stories above grade with three underground levels, the facility will house the Australian Bragg Centre for Proton Therapy & Research and the SAiGEN Cancer Institute.

Amid sobering reports of job losses in commercial real estate, coupled with months-long construction shutdowns in major markets like Boston and New York, the life sciences sector is poised to experience a less dramatic disruption, and possibly emerge from the pandemic even stronger than it was before. “COVID is a healthcare crisis, so it needs a healthcare solution, and that life sciences and biophparma solution has to be constructed,” says Kevin Chronley, vice president of A/Z Corp. and immediate past president of the Boston Area Chapter of International Society for Pharmaceutical Engineering (ISPE). Chronley predicts that construction will run the gamut from medical device manufacturing and biopharma laboratories to education and training facilities.

Ryvu Therapeutics completed construction in June of 2020 on the R&D Center for Innovative Drugs in Krakow, Poland. Accommodating approximately 300 employees, the $20 million headquarters and research facility will enable the clinical-stage biopharmaceutical company to accelerate the development of novel small molecule therapies that address emerging targets in oncology.

Genomic Partnership Wales is planning to construct a research facility in Cardiff in the United Kingdom to accelerate the development of pharmaceutical therapies. Created by a consortium of government, academic, and medical partners, the project involves the redevelopment of an existing two-story building to provide leading-edge genetics labs, seminar rooms, treatment suites, offices, freezer rooms, and support. The facility will include CL2 biocontainment research suites to ensure compliance with the UK's HBN 15 regulations for pathology services.

Catalent is rapidly scaling up its manufacturing capacity in Bloomington to enable production of a SARS-CoV-2 vaccine candidate that is currently being by developed by Janssen Pharmaceuticals, a subsidiary of Johnson & Johnson. The collaboration involves joint investment from Catalent and Janssen to enable large-scale commercial manufacturing by January of 2021, with segregated cGMP production lines operating 24/7 to create approximately a billion doses.

POINT Biopharma, a clinical-stage pharmaceutical company based in Canada, is establishing its first U.S. manufacturing center in Indianapolis. The $25 million project includes the purchase and renovation of an existing 77,000-sf, food-grade structure, with additional funds to be invested in sophisticated cleanroom technologies and packaging systems. Slated for occupancy in mid-2020, the GMP facility will support the production of radioligands for POINT's innovative cancer therapies. The next-generation manufacturing center will be fully operational by 2021.

Exyte is partnering with Univercells Technologies to create modular biomanufacturing facilities to meet the increased global demand for vaccines during the SARS-CoV-2 pandemic. Exyte’s prefabricated construction system, ExyCell, is paired with Univercells’ NevoLine biomanufacturing platform which features the scale-X™ fixed-bed bioreactor at its core.