Biocontainment

The University of Southern California is planning to break ground in late 2024 on the $315 million Discovery and Translational Hub on its Health Sciences Campus in Los Angeles. Designed by SmithGroup, the seven-story, 250,000-gsf building will provide advanced biomedical research environments in a ratio of 75 percent wet lab to 25 percent dry lab. Sited atop two additional levels of subterranean shell space, the 150,00-asf facility will include collaboration areas, offices, meeting venues, a biorepository, and a core lab for medicinal chemistry.

The University of Louisiana at Lafayette began construction in June of 2024 on a significant expansion of the New Iberia Research Center, the nation's largest facility for nonhuman primates. Creating an onsite BSL-3 laboratory for the study of infectious diseases and select agents, the $25 million project will enable the development of novel vaccines, diagnostics, and mitigation solutions. Paul J.

WACKER opened the mRNA Competence Center in June of 2024 in Halle an der Saale, Germany. Representing an investment of over €100 million, the next-generation facility enables the large-scale production of active ingredients based on messenger ribonucleic acid (mRNA). The building spans a total floor area of 79,653 sf and accommodates four new lines supported by advanced infrastructure, including 17,222 sf of glass-enclosed cleanroom space for bioprocessing under controlled conditions. 

Cincinnati Children’s Hospital Medical Center began construction in June of 2024 on the Applied Gene and Cell Therapy Center in Sharonville, Ohio. The $60 million project will transform an existing structure into a catalyst for innovative clinical trials. Designed by BHDP Architecture, the 111,000-sf facility will advance the development, testing, and manufacture of new medicines and biological therapies.

Sanofi opened a 20,000-sf biomanufacturing center in May of 2024 in Toronto. Producing adult and pediatric vaccines for pertussis, diphtheria, and tetanus, the project significantly increases capacity to meet growing demand in Canada and around the world. The next-generation facility features advanced bioprocessing suites supported by highly efficient infrastructure. Commissioning is currently under way, with full operations slated to commence in mid-2025.

The U.S. Department of Agriculture broke ground in May of 2024 on the $160 million National Center for Resilient and Regenerative Precision Agriculture (NCRRPA). Created in partnership with the University of Nebraska–Lincoln, the transformative development will enable the Agricultural Research Service to explore new solutions for sustainable crop production, water management, and animal husbandry.

Many Veterinary Diagnostic Laboratories face operational challenges stemming from their aging facilities, which can jeopardize the biosafety and biosecurity of their environment and hinder testing efficacy and turnaround times. Key strategies to modernizing these facilities include evaluating and improving sample receiving protocols and personnel/material circulation, as well as spatial planning and process optimization of the necropsy operation. These steps are aimed at improving the efficacy and efficiency of diagnostic services; achieving necessary biosecurity and biosafety standards; and attaining accreditation from the American Association of Veterinary Laboratory Diagnosticians and the National Animal Health Laboratory Network. 

The International Society for Pharmaceutical Engineering (ISPE) has announced the 2024 Facility of the Year Awards category winners. The awards include:

Increasing demand for BSL-3 and ABSL-3 lab space in the wake of the COVID-19 pandemic is driving up interest in renovating existing research facilities to accommodate these high-containment spaces. Even a small BSL-3 lab can be a costly undertaking, with special attention required for security of both personnel and biohazards, location in the building, and waste disposal, as well as the design and commissioning of exhaust system.

Texas A&M University is constructing the $49.9 million Nursing Education and Research Building in McAllen. Designed by Page, the three-story, 61,000-sf facility will address a crucial need for skilled healthcare professionals by improving access to learning opportunities in the Rio Grande Valley. The flexible, technology-enabled structure will provide a 10,000-sf clinical simulation center, four nursing classrooms, and areas for informal interaction and study.

Washington University in St. Louis opened the $616 million Jeffrey T. Fort Neuroscience Research Building in January of 2024. Designed by Perkins&Will and CannonDesign, the 608,825-sf facility provides interactive lab neighborhoods where up to 120 teams can engage in collaborative discovery. An 11-story, 584,050-sf research tower is capable of accommodating up to 1,000 investigators from the departments of neurology, neuroscience, neurosurgery, psychiatry, and anesthesiology.

Global pharmaceutical firm XBiotech will break ground in early 2024 on an expansion of its Austin campus. Designed by MOD Architecture, the 46,000-sf R&D center will catalyze the discovery and development of innovative biomedical therapies, as well as accelerating the commercialization of the company’s Natrunix rheumatology treatment. Wet laboratories for infectious disease research will foster the creation of new vaccines and medications to address emerging health challenges.  

The Vaccine and Infectious Disease Organization (VIDO), is becoming Canada’s Centre for Pandemic Research, preparing Canada for emerging health threats by expanding its expertise and infrastructure. This includes opening a new Vaccine Development Centre (VDC) to manufacture vaccines; constructing a new multispecies animal housing facility; enhancing its biosafety containment to the highest level to facilitate research on the most complex pathogens; and using its nearly five decades of success to attract top scientists. 

Louisiana State University Health Shreveport celebrated the completion of the $79 million Center for Medical Education in December of 2023. Designed by Perkins&Will and Coleman Partners Architects, the four-story, 155,000-sf facility features a 500-seat auditorium-in-the-round, three 250-seat active learning classrooms, and 27 flexible instructional venues. Simulation suites and clinical skills labs leverage immersive technologies to enhance experiential education and training.

Prince Street Partners is planning a 282,000-sf life science complex in Redwood City, Calif. Designed by Brick, now part of HGA, the project involves the adaptive reuse of an existing 85,000-sf building and the demolition of two other structures. A new five-story, 197,000-sf facility sited atop a two-level garage will be constructed to provide leasable lab and office environments for BSL-1 and BSL-2 research programs.