Genomics

Amicus Therapeutics is creating the Global Research and Gene Therapy Center of Excellence in Philadelphia. The 75,000-sf facility will provide collaborative laboratories and offices for the discovery and development of treatments for rare metabolic diseases. Accommodating up to 200 employees, the center will serve as the headquarters for the global Amicus science organization and the gene therapy division’s leadership team. Occupancy is expected in the second half of 2019.

Akouos, a genetic medicine company, has leased 37,500 sf in Boston for its research headquarters. The facility is located in a two-story, 150,000-sf building at 645 Summer Street and will support the discovery and commercialization of therapies for hearing disorders. The project was developed by Pappas Enterprises and renovated by Tocci Building Corporation. The sustainably designed structure has attained LEED Silver certification.

The Integrated Research and Innovation Center (IRIC) at the University of Idaho houses more than 20 grant-funded teams of faculty and graduate and undergraduate researchers, representing every college at the university, who collaborate on cross-department research in the hard sciences, social sciences, and humanities. No one “owns” any space in the building; instead, teams rotate in and out of the facility based on project lifespan, from a few months to several years, requiring a flexible and adaptable design.

Brammer Bio is developing two gene therapy manufacturing facilities in Massachusetts. The company will build out 35,000 sf in an existing 50,000-sf structure in Lexington to create a cGMP manufacturing and quality control operations center. Additionally, Brammer will renovate 8,000 sf in its 66,000-sf commercial cGMP plant in Cambridge to create new production suites to support manufacturing capacity expansion. DPS Group is providing architectural and engineering services for both projects, which are slated for completion in mid-2019.

Fujifilm Cellular Dynamics is creating a stem cell manufacturing center in Madison, Wis. Located in the University Research Park, the $21 million project involves the renovation of 31,500 sf in a facility near the company's existing lab and office building. The completed biomanufacturing plant will meet the requirements of the U.S. Food and Drug Administration. Completion is expected by March of 2020.

16 Tech Community Corporation broke ground in December of 2018 on the $30 million Advanced Research and Innovation Facility in Indianapolis. The Indiana Biosciences Research Institute will lease over 67,000 sf on the first three floors of the building to accommodate researchers engaged in the study of diabetes, nutrition, and metabolics. Indiana University School of Medicine will locate the Center for Regenerative Medicine's molecular therapeutics program in 12,000 sf of the facility, which will also house the Central Indiana Corporate Partnership.

Children's National Health System broke ground in late November of 2018 on the Research and Innovation Campus in Washington. The project includes the renovation of four existing buildings located on 12 acres on the former Walter Reed Medical Center Campus. A 333,000-sf research and innovation facility will provide 158,000 sf of laboratory space for the study of pediatric genomics and precision medicine. The project will include a business incubator and 175,000 of shell space to accommodate future growth. Completion is expected in 2020.

Children's Hospital of Philadelphia completed construction of the $75 million Clinical Vector Core in November of 2018. Located on the basement level of the Colket Translational Research Building, the project provides laboratories, offices, four production suites, and cleanrooms for the manufacture of gene therapy agents for clinical trials. The 15,000-sf facility features robust environmental controls and was built at a cost of $44 million. The Clinical Vector Core is part of the Raymond G.

The University of Maryland School of Medicine opened the $305 million Health Sciences Facility III in Baltimore in October of 2018. Designed by HOK and Design Collective, the 11-story, 435,000-sf building provides wet and dry labs for biomedical research, an imaging suite, offices, collaboration spaces, and conference and seminar rooms. Accommodating 400 faculty and staff members, the facility houses over 15 research teams engaged in the study of oncology, cardiology, neurology, genomics, and regenerative medicine.

The University of Texas at Arlington opened the $125 million Science & Engineering Innovation & Research Building (SEIR) in September of 2018. Designed by ZGF Architects and Page Southerland Page to accommodate interdisciplinary biomedical research, the six-story, 229,000-sf facility includes a two-story classroom wing, a four-story research wing, and a basement laboratory level with vibration-mitigated instrumentation suites.

Atara Biotherapeutics opened a $55 million manufacturing facility in June of 2018 in Thousand Oaks, Calif. Designed by HPA Architects to meet LEED sustainable design criteria, the Atara T-cell Operations and Manufacturing (ATOM) center houses a 90,000-sf facility for the production of CAR-T allogeneic therapies, as well as additional R&D labs and offices. The project was developed by Sares-Regis Group with Atara signing a 15-year lease for the building.

The University of Connecticut celebrated the opening of the $95 million Engineering and Science Building in June of 2018 in Storrs. Designed by Mitchell Giurgola Architects, the five-story, 118,000-gsf structure provides open-concept laboratories, instructional spaces, collaboration areas, and faculty offices to accommodate STEM programs in science, technology, engineering, and mathematics.

It started, not with a budget or a space, but with an idea. Today, that idea has become seven stories of collaborative lab space for cutting-edge genomic research, called the New York Genome Center (NYGC). It happened with the help of innovative solutions that allowed a team to repurpose ordinary office space in a select but heavily regulated neighborhood. The result is a large, flexible, and productive facility that brings together laboratories, conference areas, a data center, and clinical space to encourage innovation and discovery—all while achieving LEED Gold certification.

The University of Plymouth opened the £17 million Derriford Research Facility in May of 2018 in the United Kingdom. Sited adjacent to the Peninsula Schools of Medicine and Dentistry at Plymouth Science Park, the 25,000-sf building is the headquarters of the Institute of Translational and Stratified Medicine.

The University of Utah celebrated the opening of the $55 million Gary & Ann Crocker Science Center in April of 2018 in Salt Lake City. Designed by EDA Architects to promote student-faculty interaction, the four-story STEM facility provides interdisciplinary science labs, 10 flexible classrooms, lecture halls, an atrium, and a business incubator.