Genomics

Founders of the J. Craig Venter Institute’s new 45,000-sf laboratory facility in La Jolla, Calif., aspire to create a technological marvel that not only defies the tradition of energy-intensive biological laboratories, but that also initiates a new generation of facilities that have both low environmental impact and an excellent working environment. In its founder’s words, the Institute is “a unique design that will meld the environmental philosophies of our genomics research with the sustainability goals that I believe must be part of all of our lives.”

The Vanderbilt University Medical Center VANTAGE Laboratory consolidates physically separate research facilities into one shared space in order to optimize collaboration and acceleration of new biological and clinical discoveries. The renovation of 13,300 gsf of underutilized and aged space in the original 1925 Medical Center building in the heart of the medical campus co-locates six existing cores: Genome Technology, BioVU (Vanderbilt’s DNA repository), DNA Resources, DNA Sequencing, Vanderbilt Microarray Shared Resource, and Flow Cytometry.

Nova Southeastern University will begin construction in January of 2014 on the $80 million Center for Collaborative Research in Davie, Fla. The 220,000-sf facility will provide a genomics research center, wet laboratories, and business incubator space for biotech companies.

The New York Genome Center opened its $54 million facility in Manhattan in September of 2013. Providing collaborative research space for academic and industry partners, the 172,000-sf project features wet labs and suites for bioinformatics, sequencing, and data handling. Created by a consortium of 12 institutions, the center will support advanced genomics research to create innovative therapeutic solutions.

The Vaccine and Gene Therapy Institute of Florida (VGTI), an offshoot of the VGTI at Oregon Health and Science University, is dedicated to developing vaccines and immunotherapies to combat diseases such as AIDS, cancer, tuberculosis, and diseases associated with emerging viral infections such as Dengue fever and pandemic influenza. The three-story, 101,000-sf facility contains 11,000 nsf of vivarium/containment space with integrated procedure and in-vivo imaging spaces, nine bioscience research lab groups, specialty support labs, offices, and conference space.

The recently opened Translational Research Institute (TRI) in Brisbane, Australia, combines four major research institutes into a single medical and biopharmaceutical research facility where new treatments can be developed, manufactured, and clinically tested in one location, greatly shortening the time between discovery and application.

Washington University School of Medicine in St Louis is planning to break ground on a $75 million research building in summer of 2013. The 138,000-sf interdisciplinary facility will provide flexible, open labs for the Center for Genome Sciences & Systems Biology and the departments of medicine, genetics, and developmental biology. The design team includes Goody Clancy of Boston in association with Christner of St. Louis. Clayco is the general contractor. Completion is expected in June of 2015.

Emory University began occupying the $90 million Health Sciences Research Building in Atlanta in June of 2013. Designed by ZGF Architects and built by Brasfield & Gorrie, the 200,000-sf facility provides open labs for research on immunology and vaccines, neurosciences, drug discovery, pediatric health, cancer, gastroenterology, biomedical engineering, and human genetics.

The University at Albany opened a $9.4 million biomedical laboratory in June of 2013. Accommodating 60 researchers, the collaborative 15,000-sf facility provides five 1,000-sf labs, advanced imaging equipment, and glass-walled offices for the RNA Institute. The project was built by AOW Associates with fully mobile lab benches for ease of reconfiguration. LEED Silver sustainable design certification will be sought for the facility, which features a heat recovery system, sophisticated building controls, and abundant natural light.

The Clara Christie Centre for Mouse Genomics at the University of Calgary in Alberta, Canada, provides a centralized 33,000-sf facility for the production and breeding of transgenic mice, primarily serving researchers in western Canada. The center's design and operations address the needs not only of the research community, but also its animals, researchers, and staff, resulting in lower employee turnover, injuries, and sick days.

Recent high-profile natural disasters and human-based incidents are driving vivarium facility owners to reevaluate their disaster and contingency plans. Traditional approaches to risk assessment and research preservation are often over-simplified, understaffed, and insufficiently funded. A new shift in thinking focuses on preparing for the net results of losing utilities, an entire building, or access to a section of campus rather than the initial causes.

Brigham and Women's Hospital (BWH) has renovated 4,000 sf of research space to consolidate its aquaculture facilities in the Eugene Braunwald Research Center, where the environmental temperature, humidity, and lighting are regulated to sustain a successful zebrafish colony. Fixed equipment includes 96 racks capable of sustaining up to 6,600 tanks; two dedicated reverse osmosis water supply systems; and new pump and filtration systems on multiple independent circuits, with separate large-scale breeding chambers and an isolated quarantine area.

Tufts University Medford will renovate 19,627 nsf of existing wet lab space to house the Collaborative Cluster in Genome Structure and Developmental Patterning. Accommodating 70 scientists, the sustainably designed research facility will be contiguous with the Tufts Center for Regenerative and Developmental Biology. The project is supported by $9.4 million in federal stimulus funding.

The Mount Desert Island Biological Laboratory will construct the Center for Marine Functional Genomic Studies in Salisbury Cove, Maine. The 13,267-sf facility will house multidisciplinary research labs, core facilities, and support space. The building will also provide research space for Maine's IDeA Network of Biomedical Research Excellence (INBRE). The project is supported by $3.8 million in federal stimulus funding.

The University of Guelph is planning to construct the $18 million Centre for Biodiversity Genomics in Guelph, Ontario. Designed by HOK, the facility will house laboratory space for genome sequencing and bar coding. The two-story building will serve as the headquarters for the International Barcode of Life Project (iBOL).