• Addressing Biosafety Regulations with Risk Assessment and Verification Planning


    Using a verification planning process to meet current regulations—for directional airflow, atmospheric pressure reference, containment barriers, and other common compliance measures—with solutions based on risk analysis and standard operating procedures (SOPs), takes a project through planning an

  • Upgrading Facilities for No Reverse Airflow Compliance


    Bringing biosafety laboratories into compliance with the BMBL 5th Edition’s “zero airflow reversal” clause requires assessing risk appropriately, analyzing the impact of a pressure envelope on the facility, installing appropriate ventilation and control systems, and implementing new co

  • 2014 Biocontainment Facilities Priorities


    The following is a compilation of responses to a survey that asked individuals responsible for planning, design, operations, and maintenance of high-containment facilities to rank their priorities for 2014 and make open-ended comments regarding those priorities.

  • Measuring Reverse Airflow in Laboratory Failure Conditions


    A study at Yale University suggests that quantitative performance analysis of laboratory airflow may show more conclusive results than traditional methods of measurement, and thus obviate the perceived need for costly retrofits and upgrades in order to comply with the CDC/NIH’s new prohibition ag

  • Proposed ANSI Standard on BSL-3 Ventilation Systems Open for Review


    The American National Standards Institute (ANSI) will be collecting comments through Sept.

  • Best Practices for Successful Revalidation of BSL-3 Labs


    Annual revalidation of BSL-3 biocontainment facilities—which involves verifying that systems are operating to specifications—is important not only to maintain a safe working environment for scientific needs, but also to reduce utility and maintenance costs and protect the substantial financial in