Biotechnology

Autolus Therapeutics broke ground in November of 2021 on a £66 million cell manufacturing facility in Stevenage in the United Kingdom. Accommodating the production of chimeric antigen receptor T-cells for the treatment of cancer, the 80,730-sf project is being built by Merit using modular offsite construction methodology to significantly accelerate the construction timeline and reduce carbon emissions.

Amgen broke ground in November of 2021 on a $365 million biomanufacturing plant in New Albany, Ohio. Created by the design-build team of CRB and Turner Construction, the smart factory will leverage advanced automation technologies to optimize the assembly and packaging of injectable medicines. The 270,000-sf facility will accommodate 400 new employees and an array of collaborative and industrial robots.

Sterling Bay began construction in October of 2021 on a 320,000-sf life sciences center in Chicago. Designed by Gensler, the eight-story ALLY building will provide leading-edge lab and office environments for biomedical and pharmaceutical tenants. With 15’ floor-to-floor heights, the 280,000-rsf project will offer flexible floor plates of approximately 42,000 sf.

FUJIFILM Diosynth Biotechnologies broke ground in October of 2021 on a $2 billion production facility in Holly Springs, N.C. Enabling large-scale cell culture manufacturing for the creation of bulk drug substances, the structure will accommodate eight 20,000-liter bioreactors with the expansion potential for a further 24 20,000-liter bioreactors to meet market demand. Powered by clean energy, the sustainably designed complex will feature advanced systems for waste disposal and recycling.

The Davis Companies is planning to construct a three-story, 161,616-rsf research facility in Cambridge, Mass. Strategically sited in a new life sciences cluster called The Quad, the purpose-built structure will provide Class A lab and office environments for biomedical and pharmaceutical firms. Features of 101 Smith Place include:

Moderna is partnering with Alexandria Real Estate Equities to create a 462,000-rsf headquarters and research facility at the Alexandria Center development at One Kendall Square. Accelerating the discovery and development of mRNA vaccines and therapeutics, the collaborative structure will feature leading-edge R&D labs, sophisticated offices, and engaging gathering spaces.

AstraZeneca is planning to construct a $360 million manufacturing center in the Blanchardstown region of Dublin. Located on the Alexion Campus in College Park, the next-generation facility will leverage advanced process technologies and digital innovation solutions to produce small-molecule APIs (active pharmaceutical ingredients). Significantly reducing commercialization lead times, the sustainably designed structure will integrate lean manufacturing practices to lower operating costs and reduce carbon emissions.

Tonix Pharmaceuticals broke ground in August of 2021 on the 45,000-sf Advanced Development Center in Dartmouth, Mass. Enabling the production of clinical-stage vaccines for COVID-19 and other infectious diseases, the BSL-2 facility will utilize single-use bioreactors and purification suites for optimal efficiency and flexibility. The cGMP center will also offer state-of-the-art research, development, and analytical suites. Approximately 70 scientists, technicians, and manufacturing staff will work in the turnkey building. 

Ivanhoé Cambridge and Lendlease will break ground in summer of 2022 on a 320,000-sf life sciences facility in Boston. Designed by SGA, the nine-story building will provide state-of-the-art labs, offices, and collaboration spaces for biomedical and pharmaceutical tenants. Offering BSL-1 and BSL-2 research environments, the amenity-rich structure will include a multipurpose ground floor, a parking garage, and numerous outdoor areas.

The Fitzsimons Innovation Community broke ground in August of 2021 on Bioscience 5 in Aurora, Colo. Strategically located next to the University of Colorado Anschutz Medical Campus, the 90,000-sf building will enable biomedical and pharmaceutical tenants to manufacture next-generation cell and gene therapy products on a commercial scale. Saunders Construction is the general contractor for the highly flexible facility, which is slated for occupancy in spring of 2022.

The Davis Companies and Boston Development Group broke ground in August of 2021 on a purpose-built life sciences building in Watertown, Mass. The joint-venture project will offer 224,000 rsf of Class A research space for biomedical and pharmaceutical tenants. Designed by Elkus Manfredi Architects, the facility will provide next-generation laboratories, offices, a fitness center, a shared rooftop balcony, six private outdoor areas, and ample indoor parking accessible directly beneath the building.

Precision NanoSystems is constructing its global headquarters in Vancouver, British Columbia. Located in the four-story Evolution Block building, the 75,000-sf leased facility will feature a GMP biomanufacturing center for the production of genetic medicines and RNA-based therapeutics. The federal government has contributed CAD$25.1 million in funding towards the project's construction to increase the nation's domestic supply of COVID-19 vaccines and prepare for future pandemics.

Landmark Bio began construction in July of 2021 on a leased facility in Watertown, Mass. Supported by $76 million in funding, the 40,000-sf project will accelerate the availability of novel therapeutics by collocating research, development, manufacturing, and commercialization activities in the same structure. Featuring eight GMP cleanrooms configured to allow production of both cell and viral vector materials, the center will include labs, offices, and quality control suites.

The Ohio State University is constructing the $237.5 million Interdisciplinary Research Facility in Columbus. Anchoring a new innovation district, the 305,000-sf building will accommodate biomedical, life sciences, engineering, and environmental science research programs. Designed by Pelli Clarke & Partners and Moody Nolan to foster interaction and collaboration, the five-story structure will provide wet labs, computational labs, core labs, a vivarium, and a variety of support spaces.

Boston Properties broke ground in July of 2021 on a $105 million life sciences facility in Waltham, Mass. Designed by Stantec, 180 CityPoint will provide leasable lab and office environments with exceptional access to natural light and views. Featuring shared meeting spaces and a collaborative co-working nexus, the six-story, 329,000-sf building will include an expansive roof deck, a food hall, a wellness center, an indoor basketball court, and a 900-car parking structure.