Pharmaceutical

Eli Lilly and Company is planning to construct an advanced manufacturing facility in Huntsville, Alabama. Representing a total investment of $6 billion, the multibuilding campus will offer over 1 million sf of space for production, laboratories, packaging, logistics, and utilities. The sophisticated development will manufacture active pharmaceutical ingredients and small molecule synthetic and peptide medicines, including the company’s first oral small molecule GLP-1 receptor agonist, orforglipron.

The University of Virginia is constructing the $350 million Paul and Diane Manning Institute for Biotechnology in Charlottesville to catalyze breakthroughs in the fields of cellular therapy, gene therapy, nanotechnology, and drug delivery. Designed by Elkus Manfredi Architects, the flexible building will provide 355,809 sf of space for leading-edge laboratories, core facilities, advanced manufacturing suites, and clinical environments.

Breakthrough Properties completed construction in November of 2025 on One Helix in the Netherlands. Strategically sited within the campus of Amsterdam University Medical Center, the purpose-built research facility will leverage connections with the surrounding academic, life sciences, and biopharma ecosystem to catalyze life-changing scientific advancements. The 70,126-sf building was designed by UNStudio to offer world-class laboratory and office environments that foster collaboration and innovation.

When it was proposed in 2019, repurposing underutilized space at the University of Georgia for an industry partner’s fermentation lab appeared to be a good deal for everyone involved. It was a win for the pharmaceutical company that wanted to contract with the university to help it develop new products and needed a fermentation lab that met, at a minimum, biosafety level 2 (BSL-2) standards. It was a plus for staff at the university’s Bioexpression and Fermentation Facility who would perform the work. It represented an advance for the university that wanted to form new industry relationships and had available space at its Athens, Ga. campus inside the Animal Health Research Center (AHRC). And it was a win for the AHRC, a 75,000-sf biocontainment facility that would host a new industry partner in addition to other laboratories performing BSL-2, animal biosafety level 2 (ABSL-2), biosafety level 3 (BSL-3), animal biosafety level 3 (ABSL-3), and animal biosafety level 3-agricultural (ABSL-3Ag) research work.

Eli Lilly and Company is constructing the $4.5 billion Lilly Medicine Foundry in Lebanon, Ind. The 1.2 million-sf center will combine research and advanced manufacturing with the latest technology to innovate new production methods and scale global access to medicines for clinical trials. Featuring a flexible layout, the seven-building complex will create various molecular therapies, including drug substances for small molecules, biologics, and nucleic acid therapeutics. 

Merck opened a filter and membrane manufacturing facility in October of 2025 in Cork, Ireland. Offering 32,291 sf of cleanroom space, the €150 million ($174.5 million) building will meet global demand in the production process of vaccines and life-changing biomedical treatments, including monoclonal antibodies and cell and gene therapies. By locating these expanded manufacturing capacities in Europe, Merck aims to reduce cross-border dependencies and ensure reliable access to critical filtration technologies.

FUJIFILM Biotechnologies opened a $3.2 billion pharmaceutical manufacturing facility in September of 2025 in Holly Springs, N.C. Integrating leading-edge equipment and technologies, the sophisticated development features eight 20,000-liter bioreactors for the production of bulk drug substances and innovative therapies. Johnson & Johnson and Regeneron have signed 10-year contracts to secure space at the 1.3 million-sf campus, which represents the largest end-to-end cell culture CDMO hub in North America. 

The University of Pittsburgh is constructing the state-of-the-art BioForge center in the Hazelwood Green development, a brownfield site site that once accommodated a steel mill. Designed by HOK, the $250 million hub will drive breakthroughs and innovations in the manufacturing of precision biological medicines to improve human health. The 185,000-sf building will fill a critical gap in the local biotechnology ecosystem by addressing production constraints and cost-based obstacles to the wide distribution and accessibility of novel treatments.

Masaryk University (MU) is constructing the MUNI BioPharma Hub to drive excellence in research, education, and innovation in Brno in the Czech Republic. Offering three underground levels and six stories above grade, the 163,504-sf project was designed by Pelčák a partner architekti to combine leading-edge scientific infrastructure with modern academic venues. 

GenesisM, a joint venture between Bain Capital and Botanic Properties, broke ground on a Class A biomanufacturing facility in July of 2025 in Bedford, Mass. Designed by Perkins&Will, the sophisticated development addresses a critical need for purpose-built life sciences infrastructure in the Greater Boston region.

Sanofi opened its new U.S. headquarters in May of 2025 at M Station West in Morristown, New Jersey. Developed by SJP Properties and Scotto Properties, the seven-story, 260,000-sf facility was designed by Gensler to collocate approximately 2,000 employees with leadership roles in business operations, finance, R&D, human resources, technology, general medicines, specialty care, vaccines, and manufacturing and supply.

Gilead Sciences is constructing the Cancer Research Center in Foster City to accelerate the creation of novel solutions for pressing medical challenges. Driven by the company's enterprise master plan, the project is part of a strategic initiative to develop an internal research infrastructure that advances discovery in key focus areas and brings new technological capabilities in-house. The 182,000-sf facility was designed by Gensler to catalyze synergies between 54 clinical programs spanning oncology, inflammation, and virology.

AstraZeneca opened a $300 million cell therapy facility in May of 2025 in Rockville, Md. Developed by Alexandria Real Estate Equites, the 84,264-rsf building features specialized environments for the production of chimeric antigen receptor therapies (CAR-T) and T-cell receptor therapies (TCR-T). Next-generation biomanufacturing suites will leverage advanced process controls to create life-saving personalized medicine treatments, spanning every step from culturing and formulation to testing.

Merck broke ground in April of 2025 on a $1 billion biologics center of excellence in Wilmington, Del. Leveraging sophisticated automation solutions and artificial intelligence technologies, the 470,000-sf facility will offer laboratory, manufacturing, and logistics capabilities. The leading-edge structure will enable the launch and commercial production of next-generation biologics and therapies, including potent antibody-drug conjugates (ADCs).

Roche announced the launch of the Roche Genentech Innovation Center in March of 2025 on Harvard’s Enterprise Research Campus in Allston. With an initial lease of 30,000 sf of lab space in the first phase of construction, Roche intends to expand their R&D presence to eventually accommodate 500 employees. The initiative will bring together cardiovascular, renal, and metabolism experts with data science and AI specialists to accelerate innovation in drug discovery and development.