Pharmaceutical

WuXi Biologics began construction in May of 2019 on a 1.3 million-sf integrated manufacturing center in Chengdu, China. Meeting the criteria of both the U.S. Food and Drug Administration and the European Medicines Agency's GMP guidelines, the biologics hub will include both drug development and commercial manufacturing facilities. Offering an initial bioreactor capacity of 48,000 liters, the project is WuXi's twelfth drug substance manufacturing plant and will use the company's open-access and proprietary platforms.

The Rosalind Franklin Institute broke ground in May of 2019 on a £40 million campus hub in Harwell in the United Kingdom. The four-story, 58,000-sf facility will provide the government-funded research center with labs, instrumentation suites, offices, and interaction spaces to support leading-edge translational medicine programs.

Bayer broke ground in May of 2019 on the $150 million Cell Culture Technology Center in Berkeley, Calif. The 40,000-sf biopharmaceutical manufacturing facility will produce advanced therapeutics for the treatment of cancer and other diseases, enabling the company to expand its biologics development and launch capabilities. Fluor Corporation is providing a single point of responsibility for engineering, procurement, construction management, commissioning, qualification, validation, and integration of the project.

Novo Nordisk's global production will be entirely powered by renewable energy by early 2020, with a ten-year goal of achieving zero carbon emissions from operations and transportation. The pharmaceutical company has made a $70 million investment in a 105-megawatt-dc solar energy installation to be built in Pender County, North Carolina.

Biotechpharma UAB is initiating an expansion of its existing manufacturing campus in Vilnius, Lithuania. The $56 million project includes construction of a leading-edge process development lab and the installation of a new line of bioreactors for microbial fermentation at the 5,000-liter scale. Flexible facility design will also allow for increased mammalian cell culture production capacities.

The new addition to the existing Pharmacy Building creates an exciting and energetic new identity for the School of Pharmacy on the Rutgers University Brunswick campus, as well as a new front door located on a main campus pathway.

Kite Pharma is planning to build a biopharmaceutical manufacturing facility in Frederick, Md. Located on a 20-acre site at the Urbana Corporate Center, the project will provide 217,000 sf of manufacturing and support space for the production of chimeric antigen receptor T (CAR T) cell therapies as well as investigational T cell receptor (TCR) cell therapies being evaluated in solid tumors. The facility will also include 62,000 sf of office space. Occupancy is expected in 2021. Kite is a subsidiary of Gilead Sciences.

Cambrex Corporation completed construction in April of 2019 on a $24 million facility for the manufacture of highly potent active pharmaceutical ingredients (HPAPIs) in Charles City, Iowa. The 6,000-sf project houses four reactors with capacities ranging from 200 to 1,000 gallons to accommodate batches from 50 to 300 kilograms. An existing small scale manufacturing area has also been reconfigured.

EMD Serono’s SagaMORE project—designed to enhance the company’s progressive work culture through employee engagement, well-being, and biophylic design features—demonstrates why human health-centered design is the new frontier in the creation of built environments. The office complex, comprising an existing office building and a recent addition, is the first new and existing building project in the U.S., and only the second in the world, to achieve WELL Gold certification from the International WELL Building Institute (IWBI).

The International Society for Pharmaceutical Engineering has announced the winners of the 2019 Facility of the Year Awards.

ONE Life Sciences is planning to construct the £40 million Bio-Therapeutics Hub for Innovation in Aberdeen in the United Kingdom. Located on the Foresterhill Health Campus, the 69,000-sf facility will provide business incubation space, leasable labs and offices for established companies, collaboration areas, conference rooms, and venues for events and colloquia.

Bluebird Bio opened a 125,000-sf gene and cell therapy manufacturing facility in March of 2019 in Durham, N.C. Representing an $80 million investment, the project is bluebird's first wholly owned facility and will support the production of lentiviral vector for clinical and commercial applications. The building, which is now substantially complete and undergoing equipment commissioning, provides multiple manufacturing suites, quality-control testing labs, and warehouse space.

Merck opened the first M Lab™ Collaboration Center in Europe in March of 2019. Located in Molsheim, France, the facility provides biopharmaceutical customers with a shared, exploratory environment where they can work with Merck scientists and engineers to accelerate the manufacture of new therapies. The 43,000-sf facility offers advanced simulation technologies in a non-GMP environment for end-to-end process development from pre-clinical through full-scale production.

Eisai is building the $100 million Center for Genetics Guided Dementia Discovery (G2D2) in Cambridge, Mass. Sited in the newly constructed Alewife Research Center, the 50,000-sf neuroscience facility will support exploratory drug research on next-generation dementia therapeutics. Featuring numerous interaction zones and huddle areas, the center will provide open offices, a collaboration hub, flexible meeting rooms, and multidisciplinary open labs for the study of biology, chemistry, and automation.

Cellectis entered into a lease agreement in March of 2019 to build the Innovative Manufacturing Plant for Allogeneic Cellular Therapies (IMPACT) in Raleigh, N.C. Designed by Laporte Euro, the facility will produce immunotherapies based on gene-edited allogeneic CAR T-cells (UCART). Colliers International assisted in the real estate transaction. In addition, Cellectis is building a 14,000-sf manufacturing facility in Paris.