Genomics

The use of animals in biomedical research, already a decades-long ethically charged issue, has come under fire in more recent years for both a lack of scientific rigor and its huge financial appetite. Concerns about waste in basic research—in animal lives, scientist time, and research costs—are mounting, particularly when investigators are unable to confirm the data and achieve the same results when replicating original experiments (either theirs or others’). The solution? Track the effects of extrinsic environmental factors that can impact an animal's behavior, health, and reproduction: temperature, humidity, light, noise, and vibration.

Imperial College London opened the £120 million Laboratory of Medical Sciences in January of 2024 on the Hammersmith Hospital Campus. Designed by Hawkins\Brown to support team science, this collaborative hub for translational research accommodates programs in genetics, sex-based disease differences, and heart and metabolic disorders. The 130,000-sf structure features highly controlled lab environments carefully interwoven with comfortable write-up spaces and shared amenities.

The University of Virginia broke ground on the $350 million Paul and Diane Manning Institute for Biotechnology in December of 2023. Located in the Fontaine Research Park in Charlottesville, the 350,000-sf project will drive innovation in the fields of cellular therapy, gene therapy, nanotechnology, and drug delivery. By collocating state-of-the-art labs and core facilities with advanced manufacturing suites and clinical environments, the four-story building will accelerate the translation of medical discoveries into new solutions for patient care.

Ancora L&G began construction in August of 2023 on a $195 million life sciences center in Providence that will provide 80,000 sf of world-class research space for the Rhode Island Department of Health. Occupying the entirety of the second and third floors, the new state health lab will feature BSL-3 suites for the detection and mitigation of infectious disease agents and environmental hazards.

Canary Wharf Group and Kadans will break ground in fall of 2023 on One North Quay, a £500 million life sciences center in London. Designed by KPF, the 823,000-sf tower will provide world-class lab and office environments for biomedical and pharmaceutical companies. Constructed to the highest technological standards, the 23-story vertical campus will leverage advanced infrastructure to accommodate the stringent demands of wet-bench chemistry and high-containment research programs.

CellCarta, a leading provider of medical laboratory services, is partnering with developer Jadco to create a 450,000-sf life sciences center in Montreal. The $350 million project will transform the former site of the Montreal Chest Institute into Inspire Bio Innovations, a biomedical hub that will catalyze the development of new therapies and precision medicine technologies.

The University of Texas Health Science Center at Houston broke ground in June of 2023 on a $299 million facility for the School of Public Health. Located in the Texas Medical Center’s Helix Park, the 350,000-sf tower will provide leading-edge research labs, collaboration spaces, and classrooms for programs in epidemiology, genetics, nutrition, health policy, data science, and health promotion. Featuring an expansive auditorium, the 10-story building will integrate advanced distance-learning technologies to enable both in-person and remote instruction.

Ultragenyx opened a 110,000-sf gene therapy manufacturing facility in June of 2023 in Bedford, Mass. Advancing the creation of innovative treatments for rare genetic diseases, the sophisticated structure enables the large-scale manufacture of clinical-stage materials and approved products based on adeno-associated viral vectors (AAV). The highly efficient building integrates the company's proprietary Pinnacle PCL™ (producer cell line) platform which delivers optimal quality and scalability while reducing costs.

Stellenbosch University opened the $66 million Biomedical Research Institute (BMRI) in Cape Town in April of 2023. Located on the Tygerburg Campus, the 354,000–sf complex leverages an open design to foster active collaboration between researchers, staff, and students as they investigate the diseases that have the greatest impact on South Africa. Housing the Centre for Epidemic Response and Innovation, this high-performance research hub features a BSL-3 laboratory spanning 6,500 sf, the largest on the continent.

Repurposing non-research facilities to house specialized life sciences and therapeutics labs is a growing trend sparked by real estate inventory and the fiscal practicality of renovation rather than new construction. The vacancy rate throughout the United States for lab space in the fourth quarter of 2022 was 6 percent versus 19.5 percent for office space, according to the Jones Lang LaSalle real estate transparency index. The vacancy rates for 2021 were less than 4 percent for labs and approximately 15 percent for offices.

Icahn School of Medicine at Mount Sinai is constructing the 65,000-sf Hamilton and Amabel James Center for Artificial Intelligence and Human Health in New York. Designed by HOK, the project includes the redevelopment of a former nursing residence into a world-class research hub that will drive innovation in genomics, precision imaging, and multiscale disease modeling. The 12-story facility will become the first of its kind within a U.S. medical school when it opens in late 2023. 

Emory University opened the $313 million Health Science Research Building II in March of 2023 in Atlanta. Designed by HOK, the 350,000-sf facility provides world-class research environments for a range of specialties including biomedical engineering, cardiovascular medicine, oncology, inflammation, immunology, and emerging infections.

The Hurley Group has transformed an existing office building in New Haven to create the Elm City Bioscience Center. Designed by Svigals + Partners, the adaptive reuse project offers over 100,000 sf of leasable research space for startup companies. Featuring BSL-1 and BSL-2 environments, the eight-story biotech hub provides lab suites with adjacent work areas, meeting rooms, and break rooms. Advanced mechanical, electrical, and plumbing systems enable the structure’s 12,000-sf floor plates to easily adapt to changing requirements and configurations.

Mispro Biotech Services is building a 10,000-sf contract vivarium in Boston's Seaport District. The state-of-the-art facility will enable life science companies of all sizes to conduct preclinical drug development studies on rodents with the support of Mispro’s husbandry services, technical expertise, and regulatory compliance oversight.

Amgen opened a 245,000-sf R&D center in South San Francisco in October of 2022. Located on the Gateway of Pacific life sciences campus in Oyster Point, the leased facility was designed by Flad Architects and developed by BioMed Realty. Featuring modular wet and molecular labs, the nine-story tower accommodates Amgen's research programs in oncology, inflammation, and cardiometabolic diseases. Flexible floor plates integrate lab and office functions, with open work spaces and movable furnishings promoting collaboration and interaction.