In an era of expanding research portfolios and heightened expectations for interdisciplinary collaboration, universities face intensifying pressure to strategically plan, manage, and optimize research space. Research facilities, wet labs, maker spaces, core facilities, and computational suites, represent some of the most limited and costly assets in the academic environment. As competition for high-quality laboratories and specialized rooms grows, institutions are re-evaluating entrenched practices, strengthening policy frameworks, and adopting data-driven systems to ensure that space is allocated efficiently, transparently, and equitably. The most successful universities treat research space not as a static inheritance but as a strategic resource that must evolve with the institution’s mission.