Laboratory: Wet

Designing higher education labs is sometimes as much about managing the chemicals that inhabit the space as it is about the scientists and their work in the lab. How hazardous are the chemicals? How are they stored, and what are the allowable quantities? How do you protect the researchers and occupants in adjacent spaces, both during normal lab operations and in an emergency? Is it possible to craft a code-compliant chemical management strategy that aligns with the current shift toward large open labs that foster interdisciplinary collaboration? 

Denver University is planning to construct the STEM Horizons building to expand and accelerate vital research in science, technology, engineering, and mathematics. Designed by Anderson Mason Dale with Research Facilities Design (RFD) as laboratory design consultant, the six-story structure will provide 87,000 sf of new and renovated space for hands-on learning, research, business incubation, and community partnerships.

Biogen is planning to centralize its operations with a 580,000-sf global headquarters in the Kendall Common development in Cambridge, Mass. Representing a 15-year lease agreement, the facility’s strategic location will strengthen existing partnerships with MIT in research, education, and commercialization, and build on Biogen’s legacy as an integral part of the Kendall Square ecosystem.

The new Research Building IV (RB4) at Nationwide Children’s Hospital (NCH) in Columbus, Ohio, provides an ideal environment for productivity, collaboration, and flexibility by using a space policy to maximize the efficient use of labs and ancillary spaces; a neighborhood floor plan; and shared resources. The 290,000-sf building, which opened in May 2023 as part of NCH’s Abigail Wexner Research Institute (AWRI), aligns with the hospital’s “one team” culture by providing opportunities for scientists to collaborate, propelling pediatric research forward and closing the gap between lab research and bedside care.

Utah State University is constructing a new facility for the College of Veterinary Medicine to advance animal health, biomedical sciences, and public health. The 106,000-sf Veterinary Medical Education Building will accommodate growing programs and drive groundbreaking research, providing comprehensive training for the professionals needed to support Utah’s agricultural sector. Representing an investment of approximately $77 million, the state-funded structure will offer an additional 4,055 sf of lab space between two teaching labs.

Though universities may update master plans every five or 10 years, many find planning works best when it is continual and flexible to accommodate program and leadership changes. A number of projects at the University of North Texas Health Science Center (HSC) in Fort Worth demonstrate the need to assess existing spaces and develop plans for growth and flexibility, as well as the benefits of building long-term relationships with architects and other vendors.

The New York City Economic Development Corporation (NYCEDC) is planning to create a vibrant destination for education, research, and innovation in Kips Bay that is supported by $1.6 billion in state and city funding. Skidmore, Owings & Merrill is the master planner for the Science Park and Research Campus (SPARC), a first-of-its-kind learning and training center that will offer up to two million sf of academic, public health, and life science space.

Moderna completed construction on a £150 million complex in the United Kingdom for the discovery and production of mRNA vaccines and therapeutics for COVID-19 and emerging respiratory health threats. Located on the Harwell Campus in Oxfordshire, the Moderna Innovation and Technology Centre (MITC) comprises two 145,000-sf buildings for research, development, and manufacturing.

The successful decarbonization of labs and other critical science environments to increase energy efficiency, occupant safety, and annual savings requires a goal-oriented project team with the cultural mindset to adopt effectual technology/engineering processes, procurement strategies, and incentive-based outcomes. Science and engineering facilities often encounter substantial obstacles, such as cost restraints, safety issues, restrictive regulations, and tight deadlines, when completing the massive energy transition necessary to decarbonize their labs. 

Southern Illinois University Edwardsville (SIUE) is building a $105 million health sciences building for the School of Pharmacy and the School of Nursing. Designed by Lamar Johnson Collaborative and Christner Architects, the 176,000-sf facility will offer teaching and research labs, a vivarium, and modern classrooms and study areas. As well as administrative offices, the three-story structure will accommodate programs in pharmacogenomics, synthetic chemistry, biochemistry, and microbiology.

The past few decades have brought myriad technological changes to our daily lives, and experts predict the pace of change will only increase—especially in the use of artificial intelligence (AI) tools. Much of the talk surrounding AI focuses on automating repetitive processes and analyzing data, which require additional computational power but not necessarily structural modifications. But emerging technologies, including AI and robotics, may require universities and companies to rethink their approach to designing and planning buildings and labs.

Texas Biomedical Research Institute (Texas Biomed), home to North America’s largest baboon population dedicated to research, has opened a new primate research facility focused on animal welfare, human safety, and operational efficiency as guiding principles. The new Animal Care Complex (ACC) includes three modular breeding and holding facilities, each with a capacity of up to 300 animals of multiple species. The spacious facility has five indoor rooms which range from 400 to 800 sf, and outdoor yards as big as 5,500 sf. 

The fast-moving nature of biotechnology innovation means architects and designers for Regeneron have to plan for researchers’ requirements to change by the time new laboratories open on the Tarrytown, N.Y., campus. The campus is undergoing a $1.8 billion expansion, adding 900,000 sf of new laboratory and office space, along with additional parking, amenities, and infrastructure to support research and development.

Missouri University of Science and Technology is planning to construct the Bioplex, a $130 million facility for advanced research and education in life sciences, biomedicine, and biomedical engineering. ZGF Architects is partnering with Christner Architects to design the 128,000-gsf structure, which represents the final phase of the Havener Arrival Complex. The multidisciplinary building will provide lab environments for 24 research teams, including wet bench labs and associated support spaces, as well as an ABSL-2 vivarium.

The vision of biomedical research as a collective effort is resoundingly clear in the $237.5 million Pelotonia Research Center, the first building to be completed in the 350-plus-acre Carmenton district on the campus of The Ohio State University (Ohio State) in Columbus. Opened in May 2023, the center integrates almost 100,000 sf of wet labs, 25,000 sf of computational labs, and 20,000 sf of core labs in a single facility designed to host interdisciplinary collaborations and public-private initiatives that focus on solving some of the most critical health challenges. With life science as the backbone of the research endeavor, current projects range from modeling cancer progressions to 3D printing of patient-specific anatomic models.